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Cancer Stem Cells and Chemosensitivity

28 May 2011

Abstract excerpt

Cancer lethality is mainly due to the onset of distant metastases and refractoriness to chemotherapy. Thus, the development of molecular targeted agents that can restore or increase chemosensitivity will provide valuable therapeutic options for cancer patients. Growing evidence indicates that a cellular subpopulation with stem cell-like features, commonly referred to as cancer stem cells (CSCs), is critical for...

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PMID: 21622723
DOI: 10.1158/1078-0432.ccr-10-2538

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