Article
Birth weight and risk of ischemic heart disease: A Mendelian randomization study.
Scientific reports - 7 Dec 2016
Au Yeung Shiu Lun, Lin Shi Lin, Li Albert Martin, Schooling C Mary
Abstract excerpt
Low birth weight is a risk factor for cardiovascular disease. However, the association could be confounded by many factors. We used Mendelian randomization to clarify the role of birth weight in ischemic heart disease (IHD) and lipids. We used all 7 single nucleotide polymorphisms (SNPs) independently contributing to birth weight at genome wide significance (p < 5 × 10-8) in separate sample instrumental variable...
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