Birth weight, childhood obesity and risk of hypertension: a Mendelian randomization study.

Abstract excerpt

PURPOSES: Observational studies indicate that birth weight and childhood obesity are associated with essential hypertension, but their causal effect on essential hypertension remains unclear. The aim of our study is to elucidate the causal relationship between birth weight, childhood obesity, and essential hypertension by Mendelian randomization (MR) with genetic variants as instrumental variables (IVs). METHODS:...

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