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Article

Smoking-associated DNA methylation markers predict lung cancer incidence.

Clinical epigenetics - 1 Jan 2016

Zhang Yan, Elgizouli Magdeldin, Schöttker Ben, Holleczek Bernd, Nieters Alexandra, Brenner Hermann

Abstract excerpt

BACKGROUND: Newly established blood DNA methylation markers that are strongly associated with smoking might open new avenues for lung cancer (LC) screening. We aimed to assess the performance of the top hits from previous epigenome-wide association studies in prediction of LC incidence. In a prospective nested case-control study, DNA methylation at AHRR (cg05575921), 6p21.33 (cg06126421), and F2RL3 (cg03636183)...

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Share to Basic Helix-Loop-Helix Transcription Factors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27924164
DOI: 10.1186/s13148-016-0292-4
PMCID: PMC5123284

Genes

AHRR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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