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Article

Polymorphisms of ABAT, SCN2A and ALDH5A1 may affect valproic acid responses in the treatment of epilepsy in Chinese.

Pharmacogenomics - 1 Dec 2016

Li Xi, Zhang Jun, Wu Xi, Yan Han, Zhang Yin, He Ruo-Hui, Tang Yong-Jun, He Yi-Jing, Tan Dan, Mao Xiao-Yuan, Yin Ji-Ye, Liu Zhao-Qian, Zhou Hong-Hao, Liu Jie

Abstract excerpt

AIM: The clinical efficacy of valproic acid (VPA) varies greatly among epileptic patients. To find the potential genetic factors related to VPA responses, the pharmacogenetics study was conducted. METHODS: Two hundred and one Chinese Han epileptic patients who were treated by VPA for at least 1 year were recruited. Up to 24 SNPs in 11 candidate genes that correlate with the metabolism, transport or target of VPA...

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Identifiers

PMID: 27918244
DOI: 10.2217/pgs-2016-0093

Genes

ABAT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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