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Article

Adiponectin alters renal calcium and phosphate excretion through regulation of klotho expression.

Kidney international - 1 Feb 2017

Rutkowski Joseph M, Pastor Johanne, Sun Kai, Park Sun K, Bobulescu I Alexandru, Chen Christopher T, Moe Orson W, Scherer Philipp E

Abstract excerpt

The kidney controls systemic calcium and phosphate levels and disturbances of its control mechanisms can lead to a variety of diseases. The insulin-sensitizing adipokine adiponectin is renoprotective and accelerates functional recovery following renal injury. However, unlike other adipokines, adiponectin is reduced in obesity. High adiponectin levels are also correlated with bone loss, suggestive of an additional...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27914707
DOI: 10.1016/j.kint.2016.09.016
PMCID: PMC5237401

Genes

FGF23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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