Article
Clonal evolution in inherited marrow failure syndromes predicts disease progression.
Hematology. American Society of Hematology. Education Program - 8 Dec 2023
Schratz Kristen E
Abstract excerpt
Progression to myelodysplastic syndromes (MDS) and acute myeloid leukemia is one of the most serious complications of the inherited bone marrow failure and MDS-predisposition syndromes. Given the lack of predictive markers, this risk can also be a source of great uncertainty and anxiety to patients and their providers alike. Recent data show that some acquired mutations may provide a window into this risk. While...
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