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Article

Recent advances in understanding clonal haematopoiesis in aplastic anaemia.

British journal of haematology - 1 May 2017

Stanley Natasha, Olson Timothy S, Babushok Daria V

Abstract excerpt

Acquired aplastic anaemia (AA) is an immune-mediated bone marrow failure disorder inextricably linked to clonal haematopoiesis. The majority of AA patients have somatic mutations and/or structural chromosomal abnormalities detected as early as at diagnosis. In contrast to other conditions linked to clonal haematopoiesis, the clonal signature of AA reflects its immune pathophysiology. The most common alterations...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28107566
DOI: 10.1111/bjh.14510
PMCID: PMC5435524

Genes

ASXL1
BCOR
BCORL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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