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Article

A brief, but comprehensive, guide to clonal evolution in aplastic anemia

30 Nov 2018

Abstract excerpt

Abstract Acquired aplastic anemia (AA) is an immune-mediated bone marrow aplasia that is strongly associated with clonal hematopoiesis upon marrow recovery. More than 70% of AA patients develop somatic mutations in their hematopoietic cells. In contrast to other conditions linked to clonal hematopoiesis, such as myelodysplastic syndrome (MDS) or clonal hematopoiesis of indeterminate potential in the elderly, the...

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PMID: 30504346
DOI: 10.1182/asheducation-2018.1.457

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