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Article

How I utilize somatic alterations in the diagnosis, risk stratification, and therapy of hypocellular bone marrow failure.

Blood - 13 Aug 2026

Groarke Emma M, Gutierrez-Rodrigues Fernanda, Patel Bhavisha A

Abstract excerpt

ABSTRACT: Hypocellular bone marrow failure (BMF) may be acquired due to immune-mediated disease, the prototype being immune aplastic anemia (IAA), or inherited, due to germ line defects in genes important for hematopoietic stem cell function and maintenance (inherited BMF syndromes [IBMFS]). Proper diagnosis of the underlying etiology of hypocellular BMF, particularly distinguishing IAA, myelodysplastic syndrome...

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Share to Anemia, Aplastic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bone Marrow Failure Disorders

Share to Clonal Hematopoiesis

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Source

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Identifiers

PMID: 42095935
DOI: 10.1182/blood.2025029923
PMCID: PMC13487490

Genes

BMF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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