Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

miRNA-181a/b Regulates Phenotypes of Vessel Smooth Muscle Cells Through Serum Response Factor.

DNA and cell biology - 1 Feb 2017

Wei Xiaoxing, Hou Xue, Li Jianhua, Liu Yongnian

Abstract excerpt

The phenotypic modulation of vessel smooth muscle cells (VSMCs) plays a crucial role in the physiological and pathological conditions of vasculature in response to local environmental changes. The phenotypic transition of VSMCs is largely modulated by the serum response factor (SRF). miR-181a and miR-181b are members of the well-studied miR-181 family and both have complementary sequence in the 3' untranslated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3' Untranslated Regions
Share to Biomarkers
Share to Cell Movement

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Proliferation

Share to MicroRNAs

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Serum Response Factor

Source

Identifiers

PMID: 27911586
DOI: 10.1089/dna.2016.3525

Genes

SRF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

miRNA-181a/b Regulates Phenotypes of Vessel Smooth Muscle Cells Through Serum Response Factor.PMID 27911586Read ↗

An overview of potential molecular mechanisms involved in VSMC phenotypic modulation.Semantic proximity Read ↗

Hypoxia-induced miR-182-5p regulates vascular smooth muscle cell phenotypic switch by targeting RGS5.Semantic proximity Read ↗

MicroRNA regulation of phenotypic transformations in vascular smooth muscle: relevance to vascular remodeling.Semantic proximity Read ↗

Regulatory mechanism of human vascular smooth muscle cell phenotypic transformation induced by NELIN.Semantic proximity Read ↗

MicroRNA regulation of smooth muscle gene expression and phenotype.Semantic proximity Read ↗

How do microRNAs affect vascular smooth muscle cell biology?Semantic proximity Read ↗

LncRNA MFRL regulates the phenotypic switch of vascular smooth muscle cells to attenuate arterial remodeling by encoding a novel micropeptide MFRLP.Semantic proximity Read ↗

SRF SUMOylation modulates smooth muscle phenotypic switch and vascular remodelingSemantic proximity Read ↗

Micromanaging vascular smooth muscle cell differentiation and phenotypic modulation.Semantic proximity Read ↗

Involvement of the MiR-181b-5p/HMGB1 Pathway in Ang II-induced Phenotypic Transformation of Smooth Muscle Cells in HypertensionSemantic proximity Read ↗

Role of specific microRNAs in regulation of vascular smooth muscle cell differentiation and the response to injury.Semantic proximity Read ↗

microRNA let-7g suppresses PDGF-induced conversion of vascular smooth muscle cell into the synthetic phenotype.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.