Article
Rituximab increases peripheral natural killer cells in patients with rheumatoid arthritis.
Clinical and experimental rheumatology - 1 Jan 2000
Giollo Alessandro, Viapiana Ombretta, Carletto Antonio, Ortolani Riccardo, Biasi Domenico, Gatti Davide, Adami Silvano, Rossini Maurizio
Abstract excerpt
OBJECTIVES: The clinical response of rituximab (RTX) is related to the degree of B cell depletion, although other circulating lymphocytes may be affected. We investigated the changes in lymphocyte sub-populations in rheumatoid arthritis (RA) patients treated with RTX and their relationship with the therapeutic response, with attention to natural killer (NK) cells. METHODS: In fifty-one RA patients peripheral...
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