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Article

Long-term repopulation of peripheral B-cell subsets after single and repeated rituximab infusions in patients with rheumatoid arthritis.

Clinical and experimental rheumatology - 1 Jan 2000

Roll Petra, Mahmood Zafar, Muhammad Khalid, Feuchtenberger Martin, Dörner Thomas, Tony Hans-Peter

Abstract excerpt

OBJECTIVES: B-cell depletion using rituximab (RTX) has proven efficacy in patients with RA. Long-term effects on the B-cell system after single and repeated treatments are sparse. Our aim was to study the effect of multiple courses of rituximab to evaluate its impact on repeated B-cell re-population capacity. METHODS: Two cohorts, altogether 20 patients with RA were included in an open label extension study with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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PMID: 25897997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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