Blood Lymphocyte Subsets for Early Identification of Non-Remission to TNF Inhibitors in Rheumatoid Arthritis.

doi:10.3389/fimmu.2020.01913

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Article

Blood Lymphocyte Subsets for Early Identification of Non-Remission to TNF Inhibitors in Rheumatoid Arthritis.

Frontiers in immunology - 1 Jan 2020

Rodríguez-Martín Eulalia, Nieto-Gañán Israel, Hernández-Breijo Borja, Sobrino Cristina, García-Hoz Carlota, Bachiller Javier, Martínez-Feito Ana, Navarro-Compán Victoria, Lapuente-Suanzes Paloma, Bonilla Gema, Pascual-Salcedo Dora, Roy Garbiñe, Jurado Teresa, Nozal Pilar, Vázquez-Díaz Mónica, Balsa Alejandro, Villar Luisa M, Plasencia-Rodríguez Chamaida

Abstract excerpt

Background: TNF inhibitors (TNFis) are widely used for the treatment of rheumatoid arthritis (RA), although the response rates to this therapy in patients with RA remains heterogeneous and < 50% achieve remission (REM). Objective: To analyze baseline peripheral blood leukocytes profiles in order to search for biomarkers identifying patients who will most likely not achieve REM under TNFi treatment. Methods: A...

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Identifiers

PMID: 32973793
DOI: 10.3389/fimmu.2020.01913
PMCID: PMC7481468

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