Article
B- and T-cell subpopulations in patients with severe idiopathic membranous nephropathy may predict an early response to rituximab.
Kidney international - 1 Jul 2017
Rosenzwajg Michelle, Languille Eva, Debiec Hanna, Hygino Joana, Dahan Karine, Simon Tabassome, Klatzmann David, Ronco Pierre
Abstract excerpt
Primary membranous nephropathy (PMN) is characterized by antibodies to the podocyte, but little is known about B- and T-cell populations and their response to rituximab is controversial. To help resolve this we compared 33 lymphocyte subpopulations and 27 cytokines/chemokines in 25 patients with severe PMN and 27 age-matched healthy individuals. At baseline, patients had a significantly increased percentage of...
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