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Article

Chromatin landscapes and genetic risk in systemic lupus.

Arthritis research & therapy - 1 Dec 2016

Hui-Yuen Joyce S, Zhu Lisha, Wong Lai Ping, Jiang Kaiyu, Chen Yanmin, Liu Tao, Jarvis James N

Abstract excerpt

BACKGROUND: Systemic lupus erythematosus (SLE) is a multi-system, complex disease in which the environment interacts with inherited genes to produce broad phenotypes with inter-individual variability. Of 46 single nucleotide polymorphisms (SNPs) shown to confer genetic risk for SLE in recent genome-wide association studies, 30 lie within noncoding regions of the human genome. We therefore sought to identify and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27906046
DOI: 10.1186/s13075-016-1169-9
PMCID: PMC5134118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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