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Article

Human Lung Tissue Transcriptome: Influence of Sex and Age

30 Nov 2016

Abstract excerpt

BACKGROUND: Sex and age strongly influence the pathophysiology of human lungs, but scarce information is available about their effects on pulmonary gene expression. METHODS: We followed a discovery-validation strategy to identify sex- and age-related transcriptional differences in lung. RESULTS: We identified transcriptional profiles significantly associated with sex (215 genes; FDR < 0.05) and age at surgery...

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Share to Epigenetics and DNA Methylation
Share to Gene expression and cancer classification
Share to Lung Cancer Treatments and Mutations

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PMID: 27902768
DOI: 10.1371/journal.pone.0167460

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