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Article

Sex-biased molecular differences in lung adenocarcinoma are ethnic and smoking specific.

BMC pulmonary medicine - 24 Mar 2023

Li Xuetao, Wei Shuquan, Deng Liaoyuan, Tao HongYan, Liu Mingkai, Zhao Ziwen, Du Xin, Li Yujun, Hou Jun

Abstract excerpt

BACKGROUND: Sex-related differences in cancer epidemiology, tumor biology, immune system activity, and pharmacogenomics have been suggested to be important considerations for precision cancer control. Here we elucidated systematically sex biases in genetic variants, gene expression profiles, and immunological landscapes of lung adenocarcinoma patients (LUADs) with different ancestry and smoking status. METHODS:...

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Identifiers

PMID: 36964522
DOI: 10.1186/s12890-023-02387-7
PMCID: PMC10039609

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