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Gene regulatory networks reveal sex difference in lung adenocarcinoma

6 Aug 2024

Abstract excerpt

BACKGROUND: Lung adenocarcinoma (LUAD) has been observed to have significant sex differences in incidence, prognosis, and response to therapy. However, the molecular mechanisms responsible for these disparities have not been investigated extensively. METHODS: Sample-specific gene regulatory network methods were used to analyze RNA sequencing data from non-cancerous human lung samples from The Genotype Tissue...

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PMID: 39107837
DOI: 10.1186/s13293-024-00634-y

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