Article
Inherited Variants in Wnt Pathway Genes Influence Outcomes of Prostate Cancer Patients Receiving Androgen Deprivation Therapy.
International journal of molecular sciences - 26 Nov 2016
Geng Jiun-Hung, Lin Victor C, Yu Chia-Cheng, Huang Chao-Yuan, Yin Hsin-Ling, Chang Ta-Yuan, Lu Te-Ling, Huang Shu-Pin, Bao Bo-Ying
Abstract excerpt
Aberrant Wnt signaling has been associated with many types of cancer. However, the association of inherited Wnt pathway variants with clinical outcomes in prostate cancer patients receiving androgen deprivation therapy (ADT) has not been determined. Here, we comprehensively studied the contribution of common single nucleotide polymorphisms (SNPs) in Wnt pathway genes to the clinical outcomes of 465 advanced...
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