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Article

Altered pattern of tumor necrosis factor-alpha production in peripheral blood monocytes from Crohn's disease.

World journal of gastroenterology - 7 Nov 2016

Loganes Claudia, Pin Alessia, Naviglio Samuele, Girardelli Martina, Bianco Anna Monica, Martelossi Stefano, Tommasini Alberto, Piscianz Elisa

Abstract excerpt

AIM: To evaluate the inflammatory state in Crohn's disease (CD) patients and correlate it with genetic background and microbial spreading. METHODS: By means of flow cytometry, production of tumor necrosis factor-alpha (TNF-α) was measured in peripheral blood monocytes from patients suffering from CD, ulcerative colitis (UC) and in healthy subjects after stimulation of the NOD2 and TLR pathways. CD patients were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27895399
DOI: 10.3748/wjg.v22.i41.9117
PMCID: PMC5107593

Genes

TNF
NOD2
LBP
TLR2
TLR3
TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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