Article
Associations between single-nucleotide polymorphisms of human exonuclease 1 and the risk of hepatocellular carcinoma.
Oncotarget - 27 Dec 2016
Tan Shengkui, Qin Ruoyun, Zhu Xiaonian, Tan Chao, Song Jiale, Qin Linyuan, Liu Liu, Huang Xiong, Li Anhua, Qiu Xiaoqiang
Abstract excerpt
Human exonuclease 1 (hEXO1) is an important nuclease involved in mismatch repair system that contributes to maintain genomic stability and modulate DNA recombination. This study is aimed to explore the associations between single-nucleotide polymorphisms (SNPs) of hEXO1 and the hereditary susceptibility of hepatocellular carcinoma (HCC). SNPs rs1047840, rs1776148, rs3754093, rs4149867, rs4149963, and of...