Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The significance of Exonuclease 1 K589E polymorphism on hepatocellular carcinoma susceptibility in the Turkish population: a case-control study.

Molecular biology reports - 1 May 2012

Bayram Süleyman, Akkız Hikmet, Bekar Aynur, Akgöllü Ersin, Yıldırım Selçuk

Abstract excerpt

Exonuclease 1 (Exo 1) is an important nuclease involved in mismatch repair system that contributes to maintain genomic stability, to modulate DNA recombination, and to mediate cell cycle arrest. A guanine (G)/adenine (A) common single nucleotide polymorphism at first position of codon 589 in Exo 1 gene determines a glutamic acid (Glu, E) to lysine (Lys, K) (K589E) aminoacidic substitution which may alter cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Substitution
Share to Carcinoma, Hepatocellular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Repair Enzymes

Share to Exodeoxyribonucleases

Share to Genetic Association Studies

Share to Genetics, Population

Share to Liver Neoplasms

Share to Turkey

Source

Identifiers

PMID: 22205538
DOI: 10.1007/s11033-011-1406-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The significance of Exonuclease 1 K589E polymorphism on hepatocellular carcinoma susceptibility in the Turkish population: a case-control study.PMID 22205538Read ↗

No association of the exonuclease 1 T439M polymorphism and risk of hepatocellular carcinoma development in the Turkish population: a case-control study.Semantic proximity Read ↗

The significance of Exo1 K589E polymorphism on cancer susceptibility: evidence based on a meta-analysis.Semantic proximity Read ↗

The exonuclease 1 Glu589Lys gene polymorphism and cancer susceptibility: evidence based on a meta-analysis.Semantic proximity Read ↗

Associations between single-nucleotide polymorphisms of human exonuclease 1 and the risk of hepatocellular carcinoma.Semantic proximity Read ↗

Single-nucleotide polymorphism of the Exo1 gene: association with gastric cancer susceptibility and interaction with smoking in Taiwan.Semantic proximity Read ↗

Potentially functional polymorphisms of EXO1 and risk of lung cancer in a Chinese population: A case-control analysis.Semantic proximity Read ↗

Impact of EXO1 polymorphism in susceptibility to colorectal cancer.Semantic proximity Read ↗

Interaction of Exo1 genotypes and smoking habit in oral cancer in Taiwan.Semantic proximity Read ↗

Exonuclease 1 is a Potential Diagnostic and Prognostic Biomarker in Hepatocellular CarcinomaSemantic proximity Read ↗

A single nucleotide polymorphism in EXO1 gene is associated with cervical cancer susceptibility in Chinese patients.Semantic proximity Read ↗

Exonuclease 1 and its versatile roles in DNA repair.Semantic proximity Read ↗

Human Exonuclease 1 (EXO1) Regulatory Functions in DNA Replication with Putative Roles in CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.