Impact of TNF-α (rs1800629) and IL-6 (rs1800795) Polymorphisms on Cognitive Impairment in Asian Breast Cancer Patients.

doi:10.1371/journal.pone.0164204

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Article

Impact of TNF-α (rs1800629) and IL-6 (rs1800795) Polymorphisms on Cognitive Impairment in Asian Breast Cancer Patients.

PloS one - 1 Jan 2016

Chae Jung-Woo, Ng Terence, Yeo Hui Ling, Shwe Maung, Gan Yan Xiang, Ho Han Kiat, Chan Alexandre

Abstract excerpt

OBJECTIVE: Expression of pro-inflammatory cytokines is influenced by single nucleotide polymorphisms (SNPs) in the promoter regions of the pro-inflammatory cytokine genes, and cytokines are associated with the occurrence of post-chemotherapy cognitive impairment. Hence, the aim of this study was to evaluate the associations between two common pro-inflammatory cytokine gene polymorphisms namely, IL6-174 (rs1800795...

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PMID: 27701469
DOI: 10.1371/journal.pone.0164204
PMCID: PMC5049844

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