Article
Pro-inflammatory cytokine genes influence the clinical features of frontotemporal lobar degeneration.
Dementia and geriatric cognitive disorders - 1 Jan 2009
Rainero Innocenzo, Rubino Elisa, Cappa Giorgetta, Rota Eugenia, Valfrè Walter, Ferrero Patrizia, Fenoglio Pierpaola, Baci Denisa, D'Amico Giuseppina, Vaula Giovanna, Gallone Salvatore, Pinessi Lorenzo
Abstract excerpt
BACKGROUND/AIMS: Recent studies suggested a role for pro-inflammatory mediators in frontotemporal lobar degeneration (FTLD). The objective of this study was to evaluate the association of functionally active polymorphisms in pro-inflammatory cytokine genes with the occurrence and the clinical features of the disease. METHODS: Using a case-control study, we compared allelic and genotypic frequencies of several...
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