Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Critical roles of conventional dendritic cells in promoting T cell-dependent hepatitis through regulating natural killer T cells.

Clinical and experimental immunology - 1 Apr 2017

Wang J, Cao X, Zhao J, Zhao H, Wei J, Li Q, Qi X, Yang Z, Wang L, Zhang H, Bai L, Wu Z, Zhao L, Hong Z, Yin Z

Abstract excerpt

Dendritic cells (DCs) play critical roles in initiating and regulating innate immunity as well as adaptive immune responses. However, the role of conventional dendritic cells (cDCs) in concanavalin A (ConA)-induced fulminant hepatitis is unknown. In this study, we demonstrated that depletion of cDCs using either CD11c-diphtheria toxin receptor transgenic mice (DTR Tg) mice or anti-CD11c antibody reduced the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adoptive Transfer
Share to Cell Communication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis

Share to Immunomodulation

Share to Inflammation Mediators

Share to Liver Failure, Acute

Share to Liver Function Tests

Share to Natural Killer T-Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 27891589
DOI: 10.1111/cei.12907
PMCID: PMC5343358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Critical roles of conventional dendritic cells in promoting T cell-dependent hepatitis through regulating natural killer T cells.PMID 27891589Read ↗

Critical roles of conventional dendritic cells in autoimmune hepatitis via autophagy regulation.Semantic proximity Read ↗

In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha.Semantic proximity Read ↗

Hepatic Dendritic Cells, the Tolerogenic Liver Environment, and Liver Disease.Semantic proximity Read ↗

A novel cell subset: interferon-producing killer dendritic cells.Semantic proximity Read ↗

Dendritic cell regulation of NK-cell responses involves lymphotoxin-α, IL-12, and TGF-β.Semantic proximity Read ↗

Plasmacytoid dendritic cells are crucial for the initiation of inflammation and T cell immunity in vivo.Semantic proximity Read ↗

Dendritic cells promote pancreatic viability in mice with acute pancreatitis.Semantic proximity Read ↗

Type I IFN-induced, NKT cell-mediated negative control of CD8 T cell priming by dendritic cells.Semantic proximity Read ↗

Conventional dendritic cells regulate the outcome of colonic inflammation independently of T cells.Semantic proximity Read ↗

IFN-γ-rich environment programs dendritic cells toward silencing of cytotoxic immune responses.Semantic proximity Read ↗

Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.Semantic proximity Read ↗

DC subsets in positive and negative regulation of immunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.