Article
Critical roles of conventional dendritic cells in autoimmune hepatitis via autophagy regulation.
Cell death & disease - 13 Jan 2020
Fan Xiaoli, Men Ruoting, Huang Chen, Shen Mengyi, Wang Tingting, Ghnewa Yasmeen, Ma Yun, Ye Tinghong, Yang Li
Abstract excerpt
Autoimmune hepatitis (AIH) is a necroinflammatory disease associated with interactive cell populations of the innate and adaptive immune systems. The contribution of conventional dendritic cells (cDCs) to AIH and the underlying mechanism remain poorly understood. The frequency of peripheral mature cDCs increased in AIH patients and was positively correlated with disease severity. In experimental autoimmune...
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