Article
DC subsets in positive and negative regulation of immunity.
Immunological reviews - 1 Mar 2010
Coquerelle Caroline, Moser Muriel
Abstract excerpt
Since their discovery in 1973, dendritic cells (DCs) have gained strong interest from immunologists because of their unique capacity to sensitize naive T cells. There is now strong evidence that cells of the dendritic family not only control immunity but also regulate responses to self and non-self, thereby avoiding immunopathology. These two complementary functions are critical to ensure the integrity of the...
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