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Article

Steroidogenic germline polymorphism predictors of prostate cancer progression in the estradiol pathway.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2014

Lévesque Eric, Laverdière Isabelle, Audet-Walsh Etienne, Caron Patrick, Rouleau Mélanie, Fradet Yves, Lacombe Louis, Guillemette Chantal

Abstract excerpt

PURPOSE: Reliable biomarkers that predict prostate cancer outcomes are urgently needed to improve and personalize treatment approaches. With this goal in mind, we individually and collectively appraised common genetic polymorphisms related to estradiol metabolic pathways to find prostate cancer prognostic markers. METHODS: The genetic profiles of 526 men with organ-confined prostate cancer were examined to find...

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Share to Cytochrome P-450 CYP1B1
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gonadal Steroid Hormones

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Share to Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

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Source

Identifiers

PMID: 24682418
DOI: 10.1158/1078-0432.CCR-13-2567

Genes

COMT
NQO1
NQO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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