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Article

Comprehensive signature analysis of drug metabolism differences in the White, Black and Asian prostate cancer patients.

Aging - 18 Jun 2021

Liu Yang, Zhou Jia-Wei, Liu Cun-Dong, Yang Jian-Kun, Liao De-Ying, Liang Zhi-Jian, Xie Xiao, Zhou Qi-Zhao, Xue Kang-Yi, Guo Wen-Bing, Xia Ming, Zhou Jun-Hao, Bao Ji-Ming, Yang Cheng, Duan Hai-Feng, Wang Hong-Yi, Huang Zhi-Peng, Zhao Shan-Chao, Chen Ming-Kun

Abstract excerpt

The drug response sensitivity and related prognosis of prostate cancer varied from races, while the original mechanism remains rarely understood. In this study, the comprehensive signature including transcriptomics, epigenome and single nucleotide polymorphisms (SNPs) of 485 PCa cases- including 415 Whites, 58 Blacks and 12 Asians from the TCGA database were analyzed to investigate the drug metabolism differences...

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Identifiers

PMID: 34148031
DOI: 10.18632/aging.203158
PMCID: PMC8266326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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