Article
The Many Faces of the Flavivirus NS5 Protein in Antagonism of Type I Interferon Signaling
23 Nov 2016
Abstract excerpt
The vector-borne flaviviruses cause severe disease in humans on every inhabited continent on earth. Their transmission by arthropods, particularly mosquitoes, facilitates large emergence events such as witnessed with Zika virus (ZIKV) or West Nile virus in the Americas. Every vector-borne flavivirus examined thus far that causes disease in humans, from dengue virus to ZIKV, antagonizes the host type I interferon...
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