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Phenotypic Plasticity Regulates Candida albicans Interactions and Virulence in the Vertebrate Host

26 May 2016

Abstract excerpt

Phenotypic diversity is critical to the lifestyles of many microbial species, enabling rapid responses to changes in environmental conditions. In the human fungal pathogen Candida albicans, cells exhibit heritable switching between two phenotypic states, white and opaque, which yield differences in mating, filamentous growth, and interactions with immune cells in vitro. Here, we address the in vivo virulence...

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PMID: 27303374
DOI: 10.3389/fmicb.2016.00780

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