Article
CALR mutations screening in wild type JAK2(V617F) and MPL(W515K/L) Brazilian myeloproliferative neoplasm patients.
Blood cells, molecules & diseases - 1 Oct 2015
Nunes Daniela Prudente Teixeira, Lima Luciene Terezina de, Chauffaille Maria de Lourdes, Mitne-Neto Miguel, Santos Marcos Tadeu dos, Cliquet Marcelo Gil, Guerra-Shinohara Elvira Maria
Abstract excerpt
Some myeloproliferative neoplasm (MPN) patients harbor JAK2(V617F) mutation, and CALR mutations were recently discovered in wild type (WT) JAK2(V617F). We evaluated the frequency and type of CALR mutations, and clinical and hematological characteristics in WT JAK2(V617F) and MPL(W515K/L) MPN patients. Sixty-five patients were included: 21 with primary myelofibrosis (PMF), 21 with myelofibrosis post-essential...
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