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Article

JAK2 V617F, MPL, and CALR Mutations in Korean Patients with Essential Thrombocythemia and Primary Myelofibrosis.

Journal of Korean medical science - 1 Jul 2015

Kim Bo Hyun, Cho Young-Uk, Bae Mi-Hyun, Jang Seongsoo, Seo Eul-Ju, Chi Hyun-Sook, Choi Yunsuk, Kim Dae-Young, Lee Jung-Hee, Lee Je-Hwan, Lee Kyoo-Hyung, Park Young-Mi, Lee Jong-Keuk, Park Chan-Jeoung

Abstract excerpt

Mutations in the calreticulin gene, CALR, have recently been discovered in subsets of patients with essential thrombocythemia (ET) or primary myelofibrosis (PMF). We investigated Korean patients with ET and PMF to determine the prevalence, and clinical and laboratory correlations of CALR/JAK2/MPL mutations. Among 84 ET patients, CALR mutations were detected in 23 (27.4%) and were associated with higher platelet...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26130950
DOI: 10.3346/jkms.2015.30.7.882
PMCID: PMC4479941

Genes

CALR
JAK2
MPL

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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JAK2 V617F, MPL, and CALR Mutations in Korean Patients with Essential Thrombocythemia and Primary Myelofibrosis.PMID 26130950Read ↗

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Frequency of Calreticulin (CALR) Mutation and Its Clinical Prognostic Significance in Essential Thrombocythemia and Primary Myelofibrosis: A Meta-analysis.Semantic proximity Read ↗

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