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Article

Mutational subtypes of JAK2 and CALR correlate with different clinical features in Japanese patients with myeloproliferative neoplasms.

International journal of hematology - 1 Jun 2018

Misawa Kyohei, Yasuda Hajime, Araki Marito, Ochiai Tomonori, Morishita Soji, Shirane Shuichi, Edahiro Yoko, Gotoh Akihiko, Ohsaka Akimichi, Komatsu Norio

Abstract excerpt

The majority of patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) harbor JAK2, CALR, or MPL mutations. We compared clinical manifestations of different subtypes of JAK2 and CALR mutations in Japanese patients with MPNs. Within our cohort, we diagnosed 166 patients as polycythemia vera (PV), 212 patients as essential thrombocythemia (ET), 23 patients as pre-primary myelofibrosis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29464483
DOI: 10.1007/s12185-018-2421-7

Genes

CALR
JAK2
MPL

Provenance

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Mutational subtypes of JAK2 and CALR correlate with different clinical features in Japanese patients with myeloproliferative neoplasms.PMID 29464483Read ↗

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