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Article

Study of CALR, MPL, and c-kit Gene Mutations in Thai Patients with JAK2 V617F Negative Myeloproliferative Neoplasms.

Asian Pacific journal of cancer prevention : APJCP - 1 May 2022

Wiriyaukaradecha Kriangpol, Nimsanor Supanee, Tantirukdham Nithiphut, Tongsom Jin, Bunyoo Chakrit, Soonklang Kamonwan, Sritana Narongrit, Auewarakul Chirayu

Abstract excerpt

OBJECTIVE: The aim of this study to determine the prevalence of CALR, MPL and c-kit gene mutations in JAK2 V617F negative-MPN patients. METHODS: The retrospective study of CALR, MPL and c-kit mutations were analyzed in 113 samples collected from March 2010 to May 2017 and identified as JAK2 V617F-negative MPN Thai patients. The samples were analysis by gel electrophoresis and direct sequencing. RESULTS: 28.3% of...

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Identifiers

PMID: 35633552
DOI: 10.31557/APJCP.2022.23.5.1671
PMCID: PMC9587876

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