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Article

Tetratricopeptide repeat domain 9A modulates anxiety-like behavior in female mice.

Scientific reports - 21 Nov 2016

Lim Lee Wei, Shrestha Smeeta, Or Yu Zuan, Tan Shawn Zheng Kai, Chung Hwa Hwa, Sun Yang, Lim Chew Leng, Khairuddin Sharafuddin, Lufkin Thomas, Lin Valerie Chun Ling

Abstract excerpt

Tetratricopeptide repeat domain 9A (TTC9A) expression is abundantly expressed in the brain. Previous studies in TTC9A knockout (TTC9A-/-) mice have indicated that TTC9A negatively regulates the action of estrogen. In this study we investigated the role of TTC9A on anxiety-like behavior through its functional interaction with estrogen using the TTC9A-/- mice model. A battery of tests on anxiety-related behaviors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27869229
DOI: 10.1038/srep37568
PMCID: PMC5116628

Genes

HTT
TPH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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