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Article

Behavioral phenotype, intestinal microbiome, and brain neuronal activity of male serotonin transporter knockout mice.

Molecular brain - 29 Mar 2023

Shoji Hirotaka, Ikeda Kazutaka, Miyakawa Tsuyoshi

Abstract excerpt

The serotonin transporter (5-HTT) plays a critical role in the regulation of serotonin neurotransmission. Mice genetically deficient in 5-HTT expression have been used to study the physiological functions of 5-HTT in the brain and have been proposed as a potential animal model for neuropsychiatric and neurodevelopmental disorders. Recent studies have provided evidence for a link between the gut-brain axis and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36991468
DOI: 10.1186/s13041-023-01020-2
PMCID: PMC10061809

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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