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Article

[Aberrant DNA methylation and its targeted therapy in acute myeloid leukemia].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 25 May 2016

Li Xueying, Zhu Lixia, Ye Xiujin

Abstract excerpt

The occurrence and development of acute myeloid leukemia (AML) is not only related to gene mutations, but also influenced by abnormal epigenetic regulation, in which DNA methylation is one of the most important mechanisms. Abnormal DNA methylation may lead to the activation of oncogene and the inactivation of tumor suppressor gene, resulting in the occurrence of leukemia. The mutations of DNA methylation enzymes...

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Share to DNA Methylation
Share to DNA Modification Methylases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Resistance, Neoplasm

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Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 27868412
DOI: 10.3785/j.issn.1008-9292.2016.07.09
PMCID: PMC10397039

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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