Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Role of MCPIP1 in the Endothelial-Mesenchymal Transition Induced by Silica.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2016

Chao Jie, Wang Xingang, Zhang Yuxia, Zhu Tiebing, Zhang Wei, Zhou Zewei, Yang Jian, Han Bing, Cheng Yusi, Tu Xiaojie, Yao Honghong

Abstract excerpt

BACKGROUND: Silicosis is characterized by the accumulation of fibroblasts and the excessive deposition of extracellular matrix. Fibroblast generation via endothelial-mesenchymal transition (EndMT) is one process responsible for this accumulation of fibroblasts. However, the mechanisms underlying EndMT remain unknown. METHODS: Human umbilical vein endothelial cells (HUVECs) were exposed to SiO2 (50 µg/cm2)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy
Share to Cardiac Myosins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Focal Adhesion Kinase 2

Share to Human Umbilical Vein Endothelial Cells

Share to Mesoderm

Share to Myosin Light Chains

Share to Ribonucleases

Share to Silicon Dioxide

Source

Identifiers

PMID: 27866190
DOI: 10.1159/000452547

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Role of MCPIP1 in the Endothelial-Mesenchymal Transition Induced by Silica.PMID 27866190Read ↗

GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosisSemantic proximity Read ↗

IL33-regulated NPM1 promotes fibroblast-to-myofibroblast transition via ERK/AP-1 signaling in silica-induced pulmonary fibrosisSemantic proximity Read ↗

p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosisSemantic proximity Read ↗

Genome-wide DNA methylation analysis in lung fibroblasts co-cultured with silica-exposed alveolar macrophagesSemantic proximity Read ↗

GREM1/PPP2R3A expression in heterogeneous fibroblasts initiates pulmonary fibrosisSemantic proximity Read ↗

Single-cell transcriptome sequencing–based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosisSemantic proximity Read ↗

Aberrant expression of miR-125a-3p promotes fibroblast activation via Fyn/STAT3 pathway during silica-induced pulmonary fibrosisSemantic proximity Read ↗

Integrative transcriptomic and proteomic analysis reveals mechanisms of silica-induced pulmonary fibrosis in ratsSemantic proximity Read ↗

Comparative RNA‐Seq transcriptome analysis on silica induced pulmonary inflammation and fibrosis in mice silicosis modelSemantic proximity Read ↗

MiR-449a regulates autophagy to inhibit silica-induced pulmonary fibrosis through targeting Bcl2Semantic proximity Read ↗

ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL- 10Semantic proximity Read ↗

Cadmium-induced activation of inflammatory cancer-associated fibroblasts-like cells enhances malignant phenotypes of lung cancer cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.