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Article

Genetic variation in the miR-708 gene and its binding targets in bipolar disorder.

Bipolar disorders - 1 Dec 2016

Fiorentino Alessia, O'Brien Niamh Louise, Sharp Sally Isabel, Curtis David, Bass Nicholas James, McQuillin Andrew

Abstract excerpt

OBJECTIVE: rs12576775 was found to be associated with bipolar disorder (BD) in a genome-wide association study (GWAS). The GWAS signal implicates genes for the microRNAs miR-708 and miR-5579 and the first exon of the Odd Oz/ten-m homolog 4 gene (ODZ4). In the present study, miR-708, its surrounding region, and its targets were analyzed for potential BD-associated functional variants. METHODS: The miR-708 gene and...

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Source

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Identifiers

PMID: 27864917
DOI: 10.1111/bdi.12448
PMCID: PMC5244671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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