Article
Long noncoding RNA HOTAIR polymorphisms and susceptibility to bipolar disorder: a preliminary case-control study.
Nucleosides, nucleotides & nucleic acids - 1 Jan 2022
Sargazi Saman, Zahedi Abghari Armin, Mirinejad Shekoufeh, Heidari Nia Milad, Majidpour Mahdi, Danesh Hiva, Saravani Ramin, Sheervalilou Roghayeh, Shakiba Mansoor, Zahedi Abghari Fateme
Abstract excerpt
Recent studies have shown that long noncoding RNAs contribute to the pathogenesis of bipolar disorder (BD). In this study, we genotyped four HOX Transcript Antisense Intergenic RNA (HOTAIR) gene polymorphisms to investigate if these variations could affect the risk of BD and its clinical subtypes. A total of 357 subjects, comprised of 194 BD patients and 163 age-matched healthy controls, were enrolled. Genotyping...
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