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Article

Detection of BRAF p.V600E Mutations in Melanoma by Immunohistochemistry Has a Good Interobserver Reproducibility.

Archives of pathology & laboratory medicine - 1 Jan 2014

Marin Cristi, Beauchet Alain, Capper David, Zimmermann Ute, Julié Catherine, Ilie Marius, Saiag Philippe, von Deimling Andreas, Hofman Paul, Emile Jean-François

Abstract excerpt

CONTEXT: Assessment of BRAF p.V600E mutational status has become necessary for treatment of patients with metastatic melanoma. Detection of p.V600E mutation by immunohistochemistry was recently reported in several tumor types. OBJECTIVE: To evaluate the interobserver reproducibility of BRAF p.V60...

Topics

DNA Mutational Analysis
Humans
Immunohistochemistry
Melanoma
Mutation
Observer Variation
Proto-Oncogene Proteins B-raf
Reproducibility of Results
Tissue Array Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23651150
DOI: 10.5858/arpa.2013-0031-OA

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-23651150-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Detection of BRAF p.V600E Mutations in Melanoma by Immunohistochemistry Has a Good Interobserver Reproducibility.PMID 23651150Read ↗

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