Article
Detection of BRAF p.V600E Mutations in Melanoma by Immunohistochemistry Has a Good Interobserver Reproducibility.
Archives of pathology & laboratory medicine - 1 Jan 2014
Marin Cristi, Beauchet Alain, Capper David, Zimmermann Ute, Julié Catherine, Ilie Marius, Saiag Philippe, von Deimling Andreas, Hofman Paul, Emile Jean-François
Abstract excerpt
CONTEXT: Assessment of BRAF p.V600E mutational status has become necessary for treatment of patients with metastatic melanoma. Detection of p.V600E mutation by immunohistochemistry was recently reported in several tumor types. OBJECTIVE: To evaluate the interobserver reproducibility of BRAF p.V600E detection by immunohistochemistry in melanoma. DESIGN: Immunohistochemistry with VE1 antibody was performed on...
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