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Article

HPV-mediated down-regulation of NOD1 inhibits apoptosis in cervical cancer

30 Jan 2020

Abstract excerpt

Cervical cancer is the fourth most common malignant tumor in women worldwide. The persistent infection of high-risk Human Papillomavirus (hrHPV) is considered to be the primary cause of this disease. As an innate immune receptor, the nucleotide-binding oligomerization domain protein-1 (NOD1) recognizes the pathogen-associated molecular pattern (PAMP), subsequently initiating immune responses. NOD1 is also...

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PMID: 32021648
DOI: 10.1186/s13027-020-0272-3

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