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Article

Respiratory syncytial virus infection augments NOD2 signaling in an IFN-β-dependent manner in human primary cells.

European journal of immunology - 1 Oct 2012

Vissers Marloes, Remijn Thijs, Oosting Marije, de Jong Dirk J, Diavatopoulos Dimitri A, Hermans Peter W M, Ferwerda Gerben

Abstract excerpt

Respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infections in infants, with remarkable variability in disease severity. An exaggerated proinflammatory response and influx of leukocytes is part of the pathogenesis of severe RSV disease. Here, we show an increase in pr...

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Source

Identifiers

PMID: 22730064
DOI: 10.1002/eji.201242396

Genes

NOD2
TLR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22730064-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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