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The Interplay between Human Cytomegalovirus and Pathogen Recognition Receptor Signaling

20 Sept 2018

Abstract excerpt

The cellular antiviral innate immune response is triggered upon recognition of specific viral components by a set of the host's cytoplasmic or membrane-bound receptors. This interaction induces specific signaling cascades that culminate with the production of interferons and the expression of interferon-stimulated genes and pro-inflammatory cytokines that act as antiviral factors, suppressing viral replication...

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PMID: 30241345
DOI: 10.3390/v10100514

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