Article
Depressive and Biopsychosocial Frailty Phenotypes: Impact on Late-life Cognitive Disorders.
Journal of Alzheimer's disease : JAD - 1 Jan 2023
Panza Francesco, Solfrizzi Vincenzo, Sardone Rodolfo, Dibello Vittorio, Castellana Fabio, Zupo Roberta, Stallone Roberta, Lampignano Luisa, Bortone Ilaria, Mollica Anita, Berardino Giuseppe, Ruan Qingwei, Altamura Mario, Bellomo Antonello, Daniele Antonio, Lozupone Madia
Abstract excerpt
In older age, frailty is a detrimental transitional status of the aging process featuring an increased susceptibility to stressors defined by a clinical reduction of homoeostatic reserves. Multidimensional frailty phenotypes have been associated with all-cause dementia, mild cognitive impairment (MCI), Alzheimer's disease (AD), AD neuropathology, vascular dementia, and non-AD dementias. In the present article, we...
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