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Article

A multi-omics study to monitor senescence-associated secretory phenotypes of Alzheimer's disease.

Annals of clinical and translational neurology - 1 May 2024

Yang Jingzhi, Zhou Yinge, Wang Tianjiao, Li Na, Chao Yufan, Gao Songyan, Zhang Qun, Wu Shuo, Zhao Liang, Dong Xin

Abstract excerpt

OBJECTIVE: Alzheimer's disease (AD) is characterized by the progressive degeneration and damage of neurons in the brain. However, developing an accurate diagnostic assay using blood samples remains a challenge in clinic practice. The aim of this study was to explore senescence-associated secretory phenotypes (SASPs) in peripheral blood using mass spectrometry based multi-omics approach and to establish diagnostic...

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Identifiers

PMID: 38605603
DOI: 10.1002/acn3.52047
PMCID: PMC11093245

Genes

AQR
CRP
ZNF587B
FN1
SAA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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