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Article

MARCO variants are associated with phagocytosis, pulmonary tuberculosis susceptibility and Beijing lineage.

Genes and immunity - 1 Dec 2016

Thuong N T T, Tram T T B, Dinh T D, Thai P V K, Heemskerk D, Bang N D, Chau T T H, Russell D G, Thwaites G E, Hawn T R, Caws M, Dunstan S J

Abstract excerpt

Macrophage receptor with collagenous structure (MARCO) has an important role in the phagocytosis of Mycobacterium tuberculosis (M. tuberculosis). We hypothesized that MARCO polymorphisms are associated with phagocytosis, tuberculosis (TB) disease susceptibility and presentation, and infecting lineage. We used a human cellular model to examine how MARCO genotype mediates the immune response; a case-control study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27853145
DOI: 10.1038/gene.2016.43
PMCID: PMC5133378

Genes

MARCO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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