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Article

Functional polymorphisms of the TLR7 and TLR8 genes contribute to Mycobacterium tuberculosis infection.

Tuberculosis (Edinburgh, Scotland) - 1 May 2016

Lai Yung-Fa, Lin Tsun-Mei, Wang Chiou-Huey, Su Pei-Yi, Wu Jiun-Ting, Lin Meng-Chih, Eng Hock-Liew

Abstract excerpt

Tuberculosis (TB) has recently re-emerged as a major global public health threat and Mycobacterium tuberculosis (MTB) is a highly successful pathogen that evolved remarkable strategies to establish persistent infection. There is strong evidence that host genetic factors influence individual susceptibility to TB. In this study, we evaluated the associations between the TLR7 and TLR8 genetic polymorphisms and TB...

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Source

Identifiers

PMID: 27156628
DOI: 10.1016/j.tube.2016.03.008

Genes

TLR7
TLR8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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